QUALITY AND PATIENT SAFETY Evaluation of a novel closed-loop total intravenous anaesthesia drug delivery system: a randomized controlled trial
نویسندگان
چکیده
Editor’s key points † Automatic feedback control depends on having a reliable, measurable control variable. † An automatic system for closed-loop administration of i.v. anaesthesia drugs was compared with manual control. † Bispectral index and a compound analgesia score were used as the target controls. † Time within excellent (≤10%) and good (11–20%) range of the two targets was better with the automatic system. Background. We have developed an automatic anaesthesia system for closed-loop administration of anaesthesia drugs. The control variables used were bispectral index (BIS) and Analgoscore for hypnosis and antinociception, respectively.
منابع مشابه
Teletherapeutic drug administration by long distance closed-loop control of propofol.
BACKGROUND The objective of this pilot study was to investigate the feasibility of an EEG-controlled closed-loop administration of propofol over a long distance of about 200 km. METHODS We performed a teletherapeutic propofol infusion during total intravenous anaesthesia with propofol in 11 patients undergoing general surgery. The teletherapeutic system consisted of a computer at the patient ...
متن کاملThe use of volatile anesthetic agents for long-term critical care sedation (VALTS): study protocol for a pilot randomized controlled trial.
BACKGROUND Sedatives are administered to 85% of intensive care unit (ICU) patients. The most commonly used sedatives are intravenous benzodiazepines and propofol. These agents are associated with over-sedation in 40 to 60% of patients, which can lead to prolonged intubation, delirium and drug-induced hypotension. Evidence is increasing that volatile anesthetic agents are associated with faster ...
متن کاملIntravenous versus Subcutaneous Drug Administration. Which Do Patients Prefer? A Systematic Review.
BACKGROUND Intravenous (IV) drug delivery is commonly used for its rapid administration and immediate drug effect. Most studies compare IV to subcutaneous (SC) delivery in terms of safety and efficacy, but little is known about what patients prefer. METHODS A systematic review was conducted by searching seven electronic databases for articles published up to February 2014. Included studies we...
متن کاملThe effect of a checklist on the quality of post-anaesthesia patient handover: a randomized controlled trial.
OBJECTIVE Patient handover is an important element of continuity, quality and safety in patient care. Handover without standardized protocols is prone to information loss and might be a possible danger to patient safety. Checklists are established methods that help to structure complex processes in other high-risk fields such as aviation. In the past few years, their implementation has attracte...
متن کاملEvaluation of a Medication Therapy Management Program in Medicare Beneficiaries at High Risk of Adverse Drug Events: Study Methods
Little is known about the effectiveness or optimal design of medication therapy management (MTM) programs as mechanisms for improving patient safety, motivating this multicenter trial sponsored by the Agency for Healthcare Research and Quality. Six hundred subjects at high risk of adverse drug events (ADEs) will be enrolled across three study sites. The study is designed as a randomized control...
متن کامل